Calcified Tissue International & Musculoskeletal Research has announced its most highly-cited reviews and original papers published in the journal in 2023-2024. The insightful reviews and exciting new research papers cover a broad range of topics within the bone and muscle field. 

Editor-in-Chief, Professor René Rizzoli, stated: “We sincerely thank the authors for their high-quality papers, which have greatly enhanced understanding and advanced knowledge in the field of bone and muscle. Their contributions have also played a vital role in increasing the journal’s impact factor and establishing it as a leading platform for state-of-the-art basic, translational, and clinical research."

We invite you to read, cite, and share the following high-impact papers: 

Top-cited reviews

• Biochemical Markers of Musculoskeletal Health and Aging to be Assessed in Clinical Trials of Drugs Aiming at the Treatment of Sarcopenia: Consensus Paper from an Expert Group Meeting Organized by ESCEO and CARES SPRL, Under the Auspices of the WHO Collaborating Center for the Epidemiology of Musculoskeletal Conditions & Aging. 
  A. Ladang, C. Beaudart, J.Y. Reginster, N. Al-Daghri, O. Bruyère, N. Burlet, M. Cesari, A. Cherubini, M.C. da Silva, C. Cooper, A.J. Cruz-Jentoft, F. Landi, A. Laslop, S. Maggi, A. Mobasheri, S. Ormarsdottir, R. Radermecker, M. Visser, M.C.P. Yerro, R. Rizzoli, E. Cavalier
• "Bone-SASP" in Skeletal Aging 
  C.L. Fang, B. Liu, M. Wan
• Metabolic Health and Disease: A Role of Osteokines? 
  A. Shimonty, L.F. Bonewald, J.R. Huot
• A Critical Review of Current Worldwide Definitions of Sarcopenia 
  H.F. Alhmly, H.F. & R.A. Fielding 
• Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity 
  J. Herrou, G. Mabilleau, J.-M. Lecerf, T. Thomas, E. Biver, J. Paccou
• The Clinical Effectiveness of Denosumab (Prolia®) for the Treatment of Osteoporosis in Postmenopausal Women, Compared to Bisphosphonates, Selective Estrogen Receptor Modulators (SERM), and Placebo: A Systematic Review and Network Meta-Analysis.
  M.R. Moshi, K. Nicolopoulos, D. Stringer, N. Ma, M. Jenal, T. Vreugdenburg
• Megakaryocyte Secreted Factors Regulate Bone Marrow Niche Cells During Skeletal Homeostasis, Aging, and Disease 
  S.J. Karnik, M.K. Nazzal, M.A. Kacena, A. Bruzzaniti
• A Dyadic Nosology for Osteogenesis Imperfecta and Bone Fragility Syndromes 2024
  D. O. Sillence 

Top-cited Original Papers

• Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk - A Longitudinal, Population-Based Study of 75-Year-Old Women
  T. K. Paulin, L.Malmgren, F.E. McGuigan, K.E. Akesson
• Metabolome-Wide Mendelian Randomization Assessing the Causal Relationship Between Blood Metabolites and Bone Mineral Density 
  S. Chen & W. He
• Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study
  P. Rufus-Membere, K.L. Holloway-Kew, A. Diez-Perez, N.M. Appelman-Dijkstra, M.L. Bouxsein, E.F. Eriksen, J.N. Farr, S. Khosla, M.A. Kotowicz, X. Nogues, M. Rubin, J.A. Pasco
• Alcohol Consumption and Measures of Sarcopenic Muscle Risk: Cross-Sectional and Prospective Associations Within the UK Biobank Study
  J. Skinner, L. Shepstone, M. Hickson, A.A. Welch
• Mitigating the Denosumab-Induced Rebound Phenomenon with Alternating Short- and Long-Acting Anti-resorptive Therapy in a Young Boy with Severe OI Type VI
  E. Seale, M.O. Molina, S. Carsen, H. Sheffield, K. Koujok, M.-E. Robinson, J. Feber, K. Smit, M. Page, S. Walker, N. Khan, V.N. Konji, F. Rauch, L.M. Ward
• Oridonin Attenuates Thioacetamide-Induced Osteoclastogenesis Through MAPK/NF-κB Pathway and Thioacetamide-Inhibited Osteoblastogenesis Through BMP-2/RUNX2 Pathway
  X. Jin, J. Xu, F. Yang, J. Chen, F. Luo, B. Xu, J. Xu
• Effect of Bone Resorption Inhibitors on Serum Cholesterol Level and Fracture Risk in Osteoporosis: Randomized Comparative Study Between Minodronic Acid and Raloxifene
  H. Ohta, Y. Uemura, T. Sone, S. Tanaka, S. Soen, S. Mori, H. Hagino, M. Fukunaga, T. Nakamura, H. Orimo, M. Shiraki & Adequate Treatment of Osteoporosis (A-TOP) research group
• Anti-RANKL Therapy Prevents Glucocorticoid-Induced Bone Loss and Promotes Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy
  S.N. Jayash, D. Hamoudi, L.A. Stephen, A. Argaw, C. Huesa, S. Joseph, S.C. Wong, J. Frenette, C. Farquharson 

 
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About Calcified Tissue International & Musculoskeletal Research
Calcified Tissue International & Musculoskeletal Research is a peer-reviewed journal that publishes original preclinical, translational and clinical research, and reviews concerning the structure and function of bone, and other musculoskeletal tissues in living organisms, as well as clinical studies of musculoskeletal disease. It includes studies of cell biology, molecular biology, intracellular signalling, and physiology, as well as research into the hormones, cytokines, and other mediators that influence the musculoskeletal system. The journal also publishes clinical studies of relevance to bone disease, mineral metabolism, muscle function, and musculoskeletal interactions. https://www.springer.com/journal/223  
Editor-in-Chief: René Rizzoli/ Musculoskeletal Research Section Editor: Roger Fielding

About IOF
The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization dedicated to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members, including committees of scientific researchers as well as more than 330 patient, medical and research organizations, work together to make fracture prevention and healthy mobility a worldwide heath care priority. https://www.osteoporosis.foundation   @iofbonehealth